Patient reported outcome measurements in chronic rhinosinusitis; assessing the correlation between RSOM-31 and VAS.

Results 705 CRS patients were included in this study (CRSwNP n=400). Correlation between mean RSOM-31 and ‘VAS overall sinus’ score showed a moderate correlation (r=0.52), as did the correlation between RSOM-31 nasal domain and ‘VAS overall sinus’ score (r=0.52). Excellent correlations between RSOM-31 and VAS were found for the comparable symptom specific questions; nasal congestion (r=0.80), rhinorrhea (r=0.83), sneezing (r=0.81), impaired sense of smell (r=0.82) and postnasal drip (r=0.86), all p-values <0.001. None of the individual RSOM-31 items correlated well with the VAS overall sinus’ score. Conclusion We found a moderate correlation between mean RSOM31 or RSOM-31 nasal domain and ‘VAS overall sinus’ score. The moderate correlation between these scores suggests patients, in both instruments, reflect different aspects of the burden of their disease. Further studies are needed to determine what patients include in their overall VAS score that is not captured with RSOM-31.